Which side is better?

is (ĭz) v. Third person singular present indicative of be. [Middle English, from Old English; see es- in Indo-European roots.] American Heritage® Dictionary of the English ... Find 46 ways to say IS, along with antonyms, related words, and example sentences at Thesaurus.com, the world's most trusted free thesaurus. The 241-horsepower, * 2.0-liter turbocharged engine of the nimble IS 300. The 260-horsepower * V6 of the capable IS 300 AWD. And the 311-horsepower * V6 of the daring IS 350 F SPORT. The 2021 IS line delivers a connection between vehicle and driver that’s more visceral than ever before. Lue uutisia Suomesta ja maailmalta heti tuoreeltaan. IS seuraa uutistilannetta ympäri vuorokauden. Is definition, 3rd person singular present indicative of be. See more. Create an account or log in to Instagram - A simple, fun & creative way to capture, edit & share photos, videos & messages with friends & family. Is definition is - present tense third-person singular of be; dialectal present tense first-person and third-person singular of be; dialectal present tense plural of be How to use is in a sentence. 29 synonyms of is from the Merriam-Webster Thesaurus, plus 60 related words, definitions, and antonyms. Find another word for is.

2021.10.27 01:29 YoyoSaboni Which side is better?

View Poll
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2021.10.27 01:29 shiboshi78 ARE YOU GUYS SEEING WHAT IM SEEING????

ARE YOU GUYS SEEING WHAT IM SEEING???? submitted by shiboshi78 to Shibainucoin [link] [comments]


2021.10.27 01:29 environmental042 Phase II Environmental Site Assessments (Phase 2 ESA)

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2021.10.27 01:29 OhPotato What's in the box? Bread

What's in the box? Bread submitted by OhPotato to dunememes [link] [comments]


2021.10.27 01:29 dead_hopscotch_mafia Apparently

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2021.10.27 01:29 Spirited_Surprise216 Internet putting out hammers today.

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2021.10.27 01:29 Worldly_Loss395 https://soundcloud.app.goo.gl/sNhw6TyVqfLtoM2q9

I’m a young artist trying to get recognition liking and commenting if you like the song will help!!
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2021.10.27 01:29 Brolylomaniac Just dark thoughts

Is it normal to think about yourself dying, thinking about how your existence won’t hurt people anymore
I tend to imagine that every day
I don’t know what to do, I keep having thoughts of me doing pedo things, and I just want to kill myself before I hurt anyone
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2021.10.27 01:29 MrHumanBtd Your username is a cuisine, what is it?

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2021.10.27 01:29 Appropriate-Lab6803 $200 more inn

$200 more inn submitted by Appropriate-Lab6803 to SHIBArmy [link] [comments]


2021.10.27 01:29 dataentrytard Enter to win a $50 Miniature Market Gift Card (10/29/2021) {WW}

Enter to win a $50 Miniature Market Gift Card (10/29/2021) {WW} submitted by dataentrytard to sweepstakes [link] [comments]


2021.10.27 01:29 Stock_Titan IOACU | Innovative International Acquisition Corp. Announces Pricing of $200 Million Initial Public Offering

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2021.10.27 01:29 J-Z-R Has anyone else noticed Vegeta has spent 8 years in the “Hyperbolic Time Chamber” in total❓

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2021.10.27 01:29 CJoker3221 Modding herb pickups

Is it actually possible to mod how much percentage you get for the herbs you pick up? I know you can just buy potions/go to Daytower etc. But is it possible?
submitted by CJoker3221 to horizon [link] [comments]


2021.10.27 01:29 EuphoricAd2668 This site pays 3x your initial, i put in 300, now at 5000 in 8 months, paying $35+ a day!

It's a rad project, i've been in it for 8 months, the company is fully doxed and extremely public/reputable. the membership is in the hundreds of thousands globally, and joining takes like 5 minutes. you dont have to sell anything, you dont have to invite anyone you dont have to do anything - except stake your USDT and sit back and get paid.
the company pays daily, and you have the option to ''rebuy'' (similar to a manual daily compound) and the company ALSO 3x's your rebuys,
so the snowball is real -
i put in 300, and signed a couple people up, friends with a little more to invest than myself -- and now i'm up to $4000 pending, 500 sitting in my wallet, and another 400 i withdrew already, again - in 8 months.
i'm playing with house money, and now friends are asking to sign up - it's the ultimate online-work / passive-income combo
Once your intital investment is out, which goes alot faster the more volume you bring in, you're in the clear and the sky's the limit,
message me to join the wave!

disclaimer: I am not selling anything, or offering anyone anything aside from information. I can show you how to sign up, and how to fund your own account and next, plug you into the massive community -- but the rest is up to you :-)
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2021.10.27 01:29 Betacord360 In search of a missionary name tag for my friend's Halloween costume.

Anyone in SLC have an old name tag they want to part with? My buddy is wanting to be a missionary for a Halloween party this Saturday. His mom hid all of his mission stuff when she realized he was distancing himself from the church and won't tell him where it is (healthy Mormon boundaries in action).
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2021.10.27 01:29 mjai1008 Anyone here tried purchasing shimano parts that is guaranteed original from Lazada and Shoppe? If there is, what is the name of the store?

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2021.10.27 01:29 nickhdfan One of the Limited Tapestry Bundled with Cheers! Artbook

One of the Limited Tapestry Bundled with Cheers! Artbook submitted by nickhdfan to Konosuba [link] [comments]


2021.10.27 01:29 dataentrytard Enter to win a $50 Miniature Market Gift Card (10/29/2021) {WW}

Enter to win a $50 Miniature Market Gift Card (10/29/2021) {WW} submitted by dataentrytard to giveaways [link] [comments]


2021.10.27 01:29 boggyfroggypoggy What's your unpopular opinion?

Can be about anything! I only recently got into The Arcana a few weeks ago, so I'd love to see some different opinions and takes on different things in The Arcana. :)
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2021.10.27 01:29 Not_Much_Pomegranate Ah, the deadliest weapon of all, immunization of deadly diseases 🤦‍♂️

Ah, the deadliest weapon of all, immunization of deadly diseases 🤦‍♂️ submitted by Not_Much_Pomegranate to facepalm [link] [comments]


2021.10.27 01:29 hoscomputer How many of you are big into Linux or computer programing ???

Idk I just want to know if I’m the only geek here or are their others like me? Also you can look at my own Linux operating system if you want Hos Os
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2021.10.27 01:29 Unlucky-Prize Live Cat Bounce - $CRTX - Solid bounce this week likely (maybe a good long term hold)

As you may have heard, CRTX took an absolute dump after hours on news that they failed their phase 3 trial of a antibiotic drug that inhibits a bacteria they believe causes Alzheimer's at least some of the time. This was all sorts of pain. RIP my 185c, and my shares hurt too. I am a committed bagholder here, and I added more capital at $14/15. I think the rational value of this stock is actually higher today than it was yesterday, probably $200 compared to the $60 we jut saw, and that the market has this completely wrong. Even if not, the bounce potential is very significant.
Also, if you want a good cause, supporting an Alzheimer's disease company that as a product that now has extremely strong evidence it can actually improve disease outcomes for 40% of the AD population is a really great cause.
Here is the reasoning...
Before the phase 3, the market was estimating perhaps a 5-7% chance they would succeed at this. This probability came from a few pieces:

  1. No one really believed their disease theory (AD is caused by a bacteria). You might generously call this a 20% chance.
  2. Even if the above might work, their drug might fail on all sorts of other reasons, or maybe their trial was too aggressive. Call this a coinflip or a bit worse.
That gets you to the 8% or so the market was estimating, with some backup indications, yielding the 60 dollar valuation (compared to the 50 to 1000 real good or homerun outcome estimates, call it $75).
The trial if it was successful, would've been a slam dunk approval of this drug, because there are currently no drugs that treat underlying Alzheimer's disease. That was speculatively worth 500-1000 a share, because it would be a twice daily oral therapy that slows or stops alzheimers....
So why is this selloff overdone if they failed their endpoints?
Because the rational chance of a drug approval is actually higher today than it was before the unknown trial results (which the market rated at 5%), but at 40% of the population.
Inside their data, they showed that 37% of their population tested positive for the bacteria in their saliva. That group had statistically significant benefit on one measure and was somewhat close on the other - but that population was underpowered!!! 57% reduction in cognitive decline!
You can see the full presentation in which they lay this out here, which shows statistical significance on outcome measures. Unlike SAVA which is more fly by night, this company hasn't engaged in P&D activities, and phase 3 is heavily monitored by the FDA. That data should be a lot more credible than inconclusive phase 2s- the numbers are there.
https://ir.cortexyme.com/static-files/2025ddbf-00dd-4375-b8b8-c681a6f88336
They were really ambiguous on the call about if they were going to seek direct approval (which would surprise to the upside if they can) or do a really quick phase 3 (which they said they were prepared to do). But, the data shows rationally, that if you throw somewhere between 500 and 1000 Alzheimer's patients at this trial, with the high dose of the drug, and they all test positive for PG, you will certainly pass the cognitive measure, and you have a very good chance of passing the daily living measure. The more you add, the faster you might get a trial outcome.
So going back to the prior values, you have:
- Chance the disease theory is correct (bacteria causes Alzheimer's) (now 100%)
- Chance the drug trial succeeds (now shown to be successful on one endpoint for sure at low population, and maybe on the other with more people or more time)
- times value of the market, which is 40% of the previous market since it only works on people with a P Gingivalis infection, which was about 40% of the test subjects)
Going through that:
  1. They proved their disease theory is correct. The bacteria, in that patient group, seems to cause/accelerate Alzheimer's. That was previously in doubt, and a major part of why people marked the stock down. So that's now 100%.
  2. They proved their drug works with the target population, mostly. Some risk there. Let's call that 65% now.
  3. The market is 37 maybe 40% of the prior.
Putting that together, if the total was 8% of the dream value before pre-trial, you now have a total of 26% of the 'dream' value, which is more like $200 bucks a share as a rational valuation, since the odds of a revised trial are now quite high. I suppose you could write that off some due to timing, but even then, it's a lot better than the $15 after hours today. This is entirely because the disease theory is now known to be correct, and the drug is clearly effective to an extent, where as that was in doubt. And the demand here is incredible - this is a drug that if you look at the data appears to more than halve the speed of degeneration for patients that have alzheimer's AND have an active p gingivalis infection in saliva.
Additionally, the company could add in some of their other products or know how or additional targeting that make this go better, and you have a surprise potential of the FDA or another regulator being friendly. And, the other parts of their pipeline target the same organism in other ways, and may be better, or stronger in combo.
Lastly, this is really sold hard, and options will boil off (which were net bearish options, so that causes reversion as people cash in), and there are a lot of shares short which will cover. And, the narrative is black as night right now. You can mostly get positive surprises from here.
I do acknowledge that there is a remaining bearish question around liver toxicity of the drug - but they addressed it in the conf call pretty clearly around 7 minutes in, and think they can work around it with test and titration, which is a not uncommon issue with slightly liver bothering drugs.
I will probably add more shares tomorrow, and/or look at longer term calls near the money. I think the bounce can be powerful. We saw a low of 12 after hours, and it recovered to the 17s by the close. It may bounce very hard in the coming days, especially of analysts come out with conviction or any mutual funds snap up shares - float is not high, it would not be hard to go up fast.
Yes, I'm a long/baggie.
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2021.10.27 01:29 Rubysamuray306 Barudis

barudis if u see this, dm me on reddit, im the guy that talked about norway...
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2021.10.27 01:29 One4All_3004 Old servers are gone!

They just reset...sad. they will prob need the next eggs to make up for the broken servers
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